Elektrovirzība (šūnu bioloģija)

Elektrovirzība šūnu bioloģijā (angļu: electrotaxis, galvanotaxis) ir šūnu vai organismu kustība, ko virza elektriskais lauks vai strāva.^[1] Elektrovirzība var izpausties dažādos veidos, tostarp kā šūnu vai organismu augšana, attīstība, kā arī aktīva vai pasīva migrācija.^[1] ^[2] Līdzstrāvas radīti elektriskie lauki dabiski rodas arī brūču dzīšanas procesā, tādējādi nodrošinot reģeneratīvo šūnu virzību brūces rajonā.^[3] ^[4]

Balstoties uz šiem novērojumiem, tiek veikti pētījumi par to, kā iespējams pielietot elektriskos laukus, lai ietekmētu brūču dzīšanu, kā arī vēža metastāzes, morfoģenēzi, neironu vadību, patogēno baktēriju kustīgumu, bioplēves veidošanos un daudzas citas bioloģiskas parādības. ^[5] ^[6] ^[7] ^[2] ^[8] ^[9] ^[10]

Atsauces

↑ ^1,0 ^1,1 Cortese, Barbara; Palamà, Ilaria Elena; D'Amone, Stefania; Gigli, Giuseppe (2014). "Influence of electrotaxis on cell behaviour". Integrative Biology 6 (9): 817–830. doi:10.1039/c4ib00142g. PMID 25058796.
↑ ^2,0 ^2,1 Chong, Poehere; Erable, Benjamin; Bergel, Alain (December 2021). "How bacteria use electric fields to reach surfaces". Biofilm 3: 100048. doi:10.1016/j.bioflm.2021.100048. PMC 8090995. PMID 33997766.
↑ Jaffe, Lionel F.; Vanable, Joseph W. (July 1984). "Electric fields and wound healing". Clinics in Dermatology 2 (3): 34–44. doi:10.1016/0738-081X(84)90025-7. PMID 6336255.
↑ Richard Nuccitelli. A Role for Endogenous Electric Fields in Wound Healing. Current Topics in Developmental Biology 58, 2003. 1–26. lpp. ISBN 978-0-12-153158-4.
↑ Carley, PJ; Wainapel, SF (July 1985). "Electrotherapy for acceleration of wound healing: low intensity direct current.". Archives of Physical Medicine and Rehabilitation 66 (7): 443–6. PMID 3893385.
↑ Gault, Walter R.; Gatens, Paul F. (1 March 1976). "Use of Low Intensity Direct Current in Management of Ischemic Skin Ulcers". Physical Therapy 56 (3): 265–269. doi:10.1093/ptj/56.3.265. PMID 1083031.
↑ Sven Olof Wikström, Paul Svedman, h; Svedman, P.; Svensson, H.; Tanweer, A. S. (January 1999). "Effect of Transcutaneous Nerve Stimulation on Microcirculation in Intact Skin and Blister Wounds in Healthy Volunteers". Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery 33 (2): 195–201. doi:10.1080/02844319950159451. PMID 10450577.
↑ Yan, Xiaolong; Han, Jing; Zhang, Zhipei; Wang, Jian; Cheng, Qingshu; Gao, Kunxiang; Ni, Yunfeng; Wang, Yunjie (January 2009). "Lung cancer A549 cells migrate directionally in DC electric fields with polarized and activated EGFRs". Bioelectromagnetics 30 (1): 29–35. doi:10.1002/bem.20436. PMID 18618607.
↑ McCaig, Colin D.; Rajnicek, Ann M.; Song, Bing; Zhao, Min (July 2005). "Controlling Cell Behavior Electrically: Current Views and Future Potential". Physiological Reviews 85 (3): 943–978. doi:10.1152/physrev.00020.2004. PMID 15987799.
↑ Berthelot, Ryan; Doxsee, Kristina; Neethirajan, Suresh (29 June 2017). "Electroceutical Approach for Impairing the Motility of Pathogenic Bacterium Using a Microfluidic Platform". Micromachines 8 (7): 207. doi:10.3390/mi8070207. PMC 6189992. PMID 30400398.

[Influence-1] 1,0 ^1,1 Cortese, Barbara; Palamà, Ilaria Elena; D'Amone, Stefania; Gigli, Giuseppe (2014). "Influence of electrotaxis on cell behaviour". Integrative Biology 6 (9): 817–830. doi:10.1039/c4ib00142g. PMID 25058796.

[:0-2] 2,0 ^2,1 Chong, Poehere; Erable, Benjamin; Bergel, Alain (December 2021). "How bacteria use electric fields to reach surfaces". Biofilm 3: 100048. doi:10.1016/j.bioflm.2021.100048. PMC 8090995. PMID 33997766.

[3] Jaffe, Lionel F.; Vanable, Joseph W. (July 1984). "Electric fields and wound healing". Clinics in Dermatology 2 (3): 34–44. doi:10.1016/0738-081X(84)90025-7. PMID 6336255.

[nuccitelli2003role-4] Richard Nuccitelli. A Role for Endogenous Electric Fields in Wound Healing. Current Topics in Developmental Biology 58, 2003. 1–26. lpp. ISBN 978-0-12-153158-4.

[5] Carley, PJ; Wainapel, SF (July 1985). "Electrotherapy for acceleration of wound healing: low intensity direct current.". Archives of Physical Medicine and Rehabilitation 66 (7): 443–6. PMID 3893385.

[6] Gault, Walter R.; Gatens, Paul F. (1 March 1976). "Use of Low Intensity Direct Current in Management of Ischemic Skin Ulcers". Physical Therapy 56 (3): 265–269. doi:10.1093/ptj/56.3.265. PMID 1083031.

[7] Sven Olof Wikström, Paul Svedman, h; Svedman, P.; Svensson, H.; Tanweer, A. S. (January 1999). "Effect of Transcutaneous Nerve Stimulation on Microcirculation in Intact Skin and Blister Wounds in Healthy Volunteers". Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery 33 (2): 195–201. doi:10.1080/02844319950159451. PMID 10450577.

[8] Yan, Xiaolong; Han, Jing; Zhang, Zhipei; Wang, Jian; Cheng, Qingshu; Gao, Kunxiang; Ni, Yunfeng; Wang, Yunjie (January 2009). "Lung cancer A549 cells migrate directionally in DC electric fields with polarized and activated EGFRs". Bioelectromagnetics 30 (1): 29–35. doi:10.1002/bem.20436. PMID 18618607.

[Controlling_Cell_Behavior_Electrica-9] McCaig, Colin D.; Rajnicek, Ann M.; Song, Bing; Zhao, Min (July 2005). "Controlling Cell Behavior Electrically: Current Views and Future Potential". Physiological Reviews 85 (3): 943–978. doi:10.1152/physrev.00020.2004. PMID 15987799.

[10] Berthelot, Ryan; Doxsee, Kristina; Neethirajan, Suresh (29 June 2017). "Electroceutical Approach for Impairing the Motility of Pathogenic Bacterium Using a Microfluidic Platform". Micromachines 8 (7): 207. doi:10.3390/mi8070207. PMC 6189992. PMID 30400398.

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